Predicting the Evolution of Psychosocial and Cognitive Difficulties in Epilepsy: A Preventive Approach

Grant number: LP0453690

Abstract

Chronic epilepsy is associated with significant psychosocial and cognitive difficulties. Research has neglected to examine how these problems evolve from the time of a first seizure, limiting our ability to predict ?at risk? patients and apply evidence-based preventive strategies. We will follow a cohort of 90 first seizure patients over two years in a prospective longitudinal investigation, mapping psychosocial and cognitive change. This study entails a multidisciplinary collaboration with industry, applying innovative psychosocial and cognitive measures that will ultimately improve the detection of adverse pharmaceutical side-effects. The project is an international first, and will provide..

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Related publications (9)

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Psychological trajectories in the year after a newly diagnosed seizure

SL Velissaris, MM Saling, MR Newton, SF Berkovic, SJ Wilson

2012-10-01

Purpose: Underdiagnosed depression and anxiety are well-recognized issues in chronic epilepsy, but the evolution of these symptoms..

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Current challenges in the practice of epilepsy surgery

JM Wrench, R Matsumoto, Y Inoue, SJ Wilson

2011-09-01

The accurate prediction of individual outcomes after epilepsy surgery represents a key challenge facing clinicians. It requires a ..

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Psychosocial outcomes of newly-diagnosed epilepsy

Sarah J Wilson

2011-01-01

It is well-established that the diagnosis of a chronic or life-threatening illness typically gives rise to signifi cant adjustment..

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Diverse perspectives on developments in epilepsy surgery

SJ Wilson, J Engel

2010-12-01

The objective of this article is to review the dramatic changes that have occurred in the field of epilepsy surgery since the foun..

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The amygdala and anxiety after epilepsy surgery

SA Halley, JM Wrench, DC Reutens, SJ Wilson

2010-08-01

The relationship between amygdalar volume and anxiety after epilepsy surgery was explored. Participants comprised patients who und..

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Profiles of psychosocial outcome after epilepsy surgery: The role of personality

SJ Wilson, JM Wrench, AM McIntosh, PF Bladin, SF Berkovic

2010-07-01

Purpose: Wehave previously found that the developmental time frame of epilepsy onset influences adult personality traits and subse..

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Cognitive complaints after a first seizure in adulthood: Influence of psychological adjustment

SL Velissaris, SJ Wilson, MR Newton, SF Berkovic, MM Saling

2009-05-01

Purpose: To examine the nature and determinants (biologic and psychological) of cognitive complaints in first-seizure patients. We..

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Personality development in the context of intractable epilepsy

SJ Wilson, JM Wrench, AM McIntosh, PF Bladin, SF Berkovic

2009-01-01

Objectives: To investigate the developmental time frame of epilepsy onset on adult personality traits of neuroticism and extravers..

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The psychological impact of a newly diagnosed seizure: Losing and restoring perceived control

SL Velissaris, SJ Wilson, MM Saling, MR Newton, SF Berkovic

2007-03-01

This study aimed to characterize the process of psychosocial adjustment following a newly diagnosed seizure. Eighty-five adult pat..

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